Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 16/20 | 0.66 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942023 | 0.90 | ADA (0.80) | ADA | |
| SCHEMBL6938239 | 0.90 | ADA (0.82) | ADAADRB1ADRB3 | |
| SCHEMBL6942036 | 0.88 | ADA (0.59) | ADAPIN1ADRB1ADRB3NTRK1 | |
| SCHEMBL6941946 | 0.87 | ADA (0.60) | ADA | |
| SCHEMBL6942599 | 0.84 | ADA (0.63) | ADAPIN1ADRB1ADRB3NTRK1 | |
| SCHEMBL6935452 | 0.80 | ADA (1.00) | ADA | |
| SCHEMBL6942384 | 0.79 | ADA (0.79) | ADA | |
| SCHEMBL6933244 | 0.79 | ADA (0.43) | ADA | |
| SCHEMBL6938246 | 0.78 | ADA (0.73) | ADAADRB1ADRB3 | |
| SCHEMBL6935383 | 0.78 | ADA (0.81) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |