Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 11/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942023 | 0.89 | ADA (0.80) | ADA | |
| SCHEMBL6935456 | 0.89 | ADA (0.80) | ADAADRB1ADRB3 | |
| SCHEMBL6942036 | 0.88 | ADA (0.59) | ADAADRB1ADRB3NTRK1NTRK2 | |
| SCHEMBL6942763 | 0.86 | ADA (0.57) | ADA | |
| SCHEMBL6941531 | 0.84 | ADA (0.66) | ADAADRB1ADRB3NTRK1NTRK2 | |
| SCHEMBL6940656 | 0.78 | ADA (0.81) | ADAADRB1ADRB3 | |
| SCHEMBL6936185 | 0.78 | ADA (0.46) | ADAMEN1KMT2A | |
| SCHEMBL6940662 | 0.78 | ADA (0.71) | ADAADRB1ADRB3 | |
| SCHEMBL6935452 | 0.78 | ADA (1.00) | ADA | |
| SCHEMBL6938246 | 0.77 | ADA (0.73) | ADAADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |