Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941543 | 1.00 | L3MBTL1 (0.37) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL11793406 | 0.97 | F2 (0.40) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL11793410 | 0.97 | F2 (0.40) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL3311147 | 0.82 | L3MBTL1 (0.33) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL3311150 | 0.82 | L3MBTL1 (0.33) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL3307989 | 0.80 | F2 (0.36) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL3307979 | 0.80 | F2 (0.36) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL25714643 | 0.79 | L3MBTL1 (0.31) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL22691650 | 0.79 | L3MBTL1 (0.35) | L3MBTL1MGLLFBP1KDM4AF2 | |
| SCHEMBL24229621 | 0.77 | HTT (0.45) | L3MBTL1MGLLALDH1A1PHGDHALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |
| US-6410790-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| EP-0367598-B1 | NOVEL PROCESS FOR THE PRODUCTION OF 4,6-DIMETHYL-7-HYDROXYNONAN-3-ONE | Philip Morris Products Inc. (US) | 1993-09-01 | — | — | EP | disclosed |
| US-4925985-A | GRIGNARD REACTION, REDUCTION, CATALYSIS | PHILIP MORRIS INCORPORATED (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0367598-A2 | Novel process for the production of 4,6-dimethyl-7-hydroxynonan-3-one | Philip Morris Products Inc. (US) | 1990-05-09 | — | — | EP | disclosed |
| EP-0147915-B1 | NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS | Kotobuki Seiyaku Co., Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |
| US-4595694-A | Peptic ulcer treatment | KOTOBUKI SEIYAKU CO. LTD. (JP) | 1986-06-17 | — | — | US | disclosed |
| EP-0147915-A1 | New azulene derivatives useful as anti-ulcerative and anti-flammatory agents | Kotobuki Seiyaku Co., Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0053756-B1 | 2,6-DIETHYL-3,5-DIMETHYL-2,3-DIHYDRO-4H-PYRAN, PROCESS FOR ITS PREPARATION AND ITS USE IN THE EARLY IDENTIFICATION AND LOCATION OF AND IN COMBATING LASIODERMA SERRICORNE F | B.A.T. Cigarettenfabriken GmbH (DE) | 1984-09-12 | — | — | EP | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0053756-A1 | 2,6-Diethyl-3,5-dimethyl-2,3-dihydro-4H-pyran, process for its preparation and its use in the early identification and location of and in combating Lasioderma serricorne F | B.A.T. Cigarettenfabriken GmbH (DE) | 1982-06-16 | — | — | EP | disclosed |
| US-4188341-A | Process for the production of (substituted) 2,6-dimethylanilines | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |