Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 4/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890961 | 0.71 | — | — | |
| SCHEMBL1884027 | 0.71 | — | — | |
| SCHEMBL1883346 | 0.71 | — | — | |
| SCHEMBL601258 | 0.69 | — | — | |
| SCHEMBL6938427 | 0.68 | GABBR2 (0.45) | GABBR2GABBR1GABRR1CYP1A2TSHR | |
| SCHEMBL8762129 | 0.67 | — | — | |
| SCHEMBL14803215 | 0.65 | GABBR2 (0.42) | GABBR2GABBR1GABRR1METAP1LAP3 | |
| SCHEMBL19697646 | 0.65 | PTGS1 (0.48) | GABBR2GABBR1GABRR1 | |
| SCHEMBL13892954 | 0.65 | PTGS1 (0.48) | GABBR2GABBR1GABRR1 | |
| SCHEMBL23995837 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003516346-A | — | — | 2003-05-13 | — | — | JP | claimed |
| EP-1239843-A1 | NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS | AstraZeneca AB (SE) | 2002-09-18 | — | — | EP | claimed |
| WO-2001041743-A1 | NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS | ASTRAZENECA AB (SE) | 2001-06-14 | — | — | WO | claimed |
| WO-2004000856-A1 | COMBINATION OF A REFLUX INHIBITOR AND AN IMIDAZOPYRIDINE FOR THE TREATMENT OF GERD | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
| WO-2002100870-A1 | NEW NAPSYLATE SALTS II | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |
| EP-1239843-A1 | NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS | AstraZeneca AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001041743-A1 | NEW (AMINOPROPYL)METHYLPHOSPHINIC ACIDS | ASTRAZENECA AB (SE) | 2001-06-14 | — | — | WO | disclosed |