Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.44 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940657 | 1.00 | LMNA (0.44) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6943894 | 0.94 | HSP90AB1 (0.43) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6943889 | 0.94 | HSP90AB1 (0.43) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL7075739 | 0.93 | LMNA (0.45) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL7074596 | 0.93 | LMNA (0.45) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6864422 | 0.91 | HSP90AB1 (0.42) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6864423 | 0.91 | HSP90AB1 (0.42) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6939405 | 0.91 | LMNA (0.41) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL7075879 | 0.91 | LMNA (0.41) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6860198 | 0.90 | LMNA (0.41) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045856-B1 | NOVEL AROMATIC AMIDES, PREPARATION METHOD AND APPLICATION AS MEDICINES | AVENTIS PHARMA SA (FR) | 2003-04-09 | — | — | EP | disclosed |