Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 18/20 | 0.55 |
| ▸ | METAP1 | P53582 | 7/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489501 | 1.00 | METAP2 (0.55) | METAP2METAP1REN | |
| SCHEMBL6565203 | 0.82 | METAP2 (0.56) | METAP2METAP1REN | |
| SCHEMBL7350349 | 0.81 | METAP2 (0.65) | METAP2METAP1REN | |
| SCHEMBL6565080 | 0.80 | METAP2 (0.62) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL7352646 | 0.80 | METAP2 (0.63) | METAP2METAP1REN | |
| SCHEMBL7453100 | 0.80 | METAP2 (0.57) | METAP2METAP1REN | |
| SCHEMBL6477548 | 0.79 | METAP2 (0.61) | METAP2METAP1REN | |
| SCHEMBL7353424 | 0.79 | METAP2 (0.69) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL7359229 | 0.78 | METAP2 (0.67) | METAP2METAP1REN | |
| SCHEMBL7353359 | 0.78 | METAP2 (0.78) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |