Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586993 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL19435708 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6936689 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8837203 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL19435722 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6708068 | 0.72 | GAA (0.57) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6647774 | 0.72 | GAA (0.57) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8465901 | 0.71 | MGAM (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL23255850 | 0.71 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21518777 | 0.71 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973768-B1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-09 | — | — | EP | claimed |
| US-4770870-A | BY ALSO ADMINISTERING A THIO COMPOUND, I.E. CYSTEINE; ANTICANCER AGENT | ASTA PHARMA AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | claimed |