SCHEMBL6936689

SCHEMBL6936689

CCOC(=O)CC[CH]NC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CYP1A2 P05177 1/20 0.42
NR1I2 O75469 1/20 0.42
PGR P06401 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
PTGS2 P35354 1/20 0.42
PDE4D Q08499 1/20 0.42
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TRPA1 O75762 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.38
CYP4F2 P78329 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586785 0.83 CYP1A2 (0.46) GAAMGAMSIMGAM2CYP1A2
SCHEMBL6942345 0.80 GAA (0.50) GAAMGAMSIMGAM2CYP1A2
SCHEMBL9183887 0.74 NR1I2 (0.60) GAAMGAMSIMGAM2CYP1A2
SCHEMBL9183882 0.74 NR1I2 (0.60) GAAMGAMSIMGAM2CYP1A2
SCHEMBL10048518 0.74 ALDH1A1 (0.50) GAAMGAMSIMGAM2CYP1A2
SCHEMBL10337356 0.73 GAA (0.42) GAAMGAMSIMGAM2CYP1A2
SCHEMBL10406961 0.73
SCHEMBL525668 0.73
SCHEMBL10012426 0.73
Succinic Acid Diethyl Ester SCHEMBL29266181 0.71 GAA (0.60) GAAMGAMSIMGAM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973768-B1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-09 EP claimed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP claimed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO claimed
US-6583164-B1 Lyophilized imidazole-1-yl or 1,2,4-triazole-1-yl quaternized with a alklycarbonyloxy alkyl group eliminated in vivo; a saccharide; 4-acetoxymethyl-1-(3-(2-oxo-3-(4-(1H-tetrazol-yl) phenyl)-1-imidazolydinyl)butyl)-1H-1,2,4-triazolium chloride TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-6407129-B1 INJECTABLE QUATERNIZED SALT FUNGICIDES; WATER SOLUBILITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-1120116-A1 ANTIMYCOTIC DRUG COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP disclosed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP disclosed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO disclosed