Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | PGC | P20142 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945023 | 0.90 | PSEN1 (0.47) | BACE1 | |
| SCHEMBL6953685 | 0.87 | CYP3A4 (0.41) | CTSDCCR1 | |
| SCHEMBL6952143 | 0.87 | CYP3A4 (0.41) | CTSDCCR1 | |
| SCHEMBL6947796 | 0.80 | CYP3A4 (0.42) | CTSDCCR1BACE1ADAM17 | |
| SCHEMBL6950300 | 0.79 | CYP3A4 (0.40) | CTSDCCR1BACE1 | |
| SCHEMBL6946694 | 0.78 | CYP3A4 (0.46) | CTSDCCR1BACE1ADAM17 | |
| SCHEMBL6953154 | 0.78 | PSEN1 (0.45) | BACE1 | |
| SCHEMBL6947880 | 0.78 | PSEN1 (0.45) | BACE1 | |
| SCHEMBL6947903 | 0.76 | CYP3A4 (0.40) | CTSDCTSEPGCCCR1 | |
| SCHEMBL6712577 | 0.76 | CCR1 (0.50) | CCR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633881-B1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LTD (HK) | 2003-10-29 | — | — | EP | claimed |
| EP-0633881-B1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LTD (HK) | 2003-10-29 | — | — | EP | disclosed |