Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.63 |
| ▸ | MMP2 | P08253 | 10/20 | 0.41 |
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 9/20 | 0.41 |
| ▸ | MMP7 | P09237 | 7/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097968 | 0.82 | ADAM17 (0.73) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6942567 | 0.82 | ADAM17 (0.73) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6942575 | 0.82 | ADAM17 (0.73) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6942562 | 0.82 | ADAM17 (0.73) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6687619 | 0.81 | ADAM17 (0.65) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6687622 | 0.81 | ADAM17 (0.65) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6943944 | 0.80 | ADAM17 (0.73) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6983457 | 0.79 | ADAM17 (0.69) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6981671 | 0.79 | ADAM17 (0.69) | ADAM17MMP2MMP1MMP8MMP13 | |
| SCHEMBL6945161 | 0.79 | ADAM17 (0.71) | ADAM17MMP2MMP1MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | claimed |