Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 17/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935340 | 0.93 | ADA (0.72) | ADA | |
| SCHEMBL6938860 | 0.88 | ADA (0.72) | ADAGRK2 | |
| SCHEMBL6941851 | 0.87 | ADA (0.79) | ADAADRB2 | |
| SCHEMBL6942581 | 0.87 | ADA (0.81) | ADAADRB2 | |
| SCHEMBL6938186 | 0.86 | ADA (0.62) | ADA | |
| SCHEMBL6941844 | 0.85 | ADA (1.00) | ADAADRB2 | |
| SCHEMBL6940669 | 0.84 | ADA (0.52) | ADA | |
| SCHEMBL6936072 | 0.83 | ADA (0.72) | ADA | |
| SCHEMBL6935339 | 0.82 | ADA (0.51) | ADA | |
| SCHEMBL6940673 | 0.80 | ADA (0.56) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |