Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 13/20 | 0.72 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935340 | 0.90 | ADA (0.72) | ADAPLA2G2A | |
| SCHEMBL6942584 | 0.88 | ADA (0.73) | ADAGRK2 | |
| SCHEMBL6938186 | 0.87 | ADA (0.62) | ADA | |
| SCHEMBL6940669 | 0.87 | ADA (0.52) | ADA | |
| SCHEMBL6938856 | 0.86 | ADA (0.80) | ADAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6939875 | 0.86 | ADA (0.78) | ADAGRK2PLA2G2ANQO2MTNR1A | |
| SCHEMBL6935339 | 0.84 | ADA (0.51) | ADA | |
| SCHEMBL6939869 | 0.84 | ADA (1.00) | ADA | |
| SCHEMBL6936293 | 0.83 | ADA (0.73) | ADAGRK2NQO2MTNR1AMTNR1B | |
| SCHEMBL6941259 | 0.83 | ADA (0.71) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |