Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.44 |
| ▸ | HMGCR | P04035 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911577 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL157361 | 1.00 | — | — | |
| SCHEMBL1332658 | 1.00 | — | — | |
| SCHEMBL154927 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL15978 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL4879841 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL9234866 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL177432 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL371425 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL | |
| SCHEMBL18911556 | 1.00 | TSHR (0.50) | TSHRTHRBPTPN7HMGCRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081408-A9 | G-PROTEIN COUPLED RECEPTOR (GPCR) AGONISTS AND ANTAGONISTS AND METHODS OF ACTIVATING AND INHIBITING GPCR USING THE SAME | NEW ENGLAND MEDICAL CT (US) | 2003-01-03 | — | — | WO | disclosed |