SCHEMBL177432

SCHEMBL177432

CCCCCCCCCCCCCCCCCCCCC[C]=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.50
PTPN7 P35236 4/20 0.44
HMGCR P04035 2/20 0.44
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
EPHX2 P34913 1/20 0.39
ALDH1A1 P00352 2/20 0.38
DNM1 Q05193 1/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911577 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL157361 1.00
SCHEMBL1332658 1.00
SCHEMBL154927 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL15978 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL4879841 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL9234866 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL371425 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL6942814 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL18911556 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137663-A2 TREATMENT OF DKK2 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-06-27 WO claimed
WO-2024129886-A2 TREATMENT OF MST1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-06-20 WO claimed
WO-2024118979-A1 TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-06-06 WO claimed
US-20240175031-A1 TREATMENT OF MST1 RELATED DISEASES AND DISORDERS EMPIRICO INC. 2024-05-30 US claimed
EP-4359535-A1 TREATMENT OF DKK2 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-05-01 EP claimed
EP-4358932-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-05-01 EP claimed
EP-4355429-A1 TREATMENT OF MST1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-04-24 EP claimed
EP-4355355-A1 TREATMENT OF PLIN1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-04-24 EP claimed
EP-4355430-A1 TREATMENT OF MST1R RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-04-24 EP claimed
EP-4355878-A1 TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2024-04-24 EP claimed
WO-1991012305-A1 OIL REMOVAL NOVO NORDISK A/S (DK) 1991-08-22 WO claimed
WO-1990014429-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1990-11-29 WO claimed
WO-1990009451-A1 A PROCESS FOR PRODUCING GLYCOSIDE ESTERS AND COMPOSITIONS COMPRISING GLYCOSIDE ESTERS NOVO NORDISK A/S (DK) 1990-08-23 WO claimed
EP-0115816-B1 NEW AMINOGLYCOSIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-08-03 EP claimed
US-4725582-A IMMUNE RESPONSE ENHANCERS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1988-02-16 US claimed
US-4554269-A ANTIVIRAL ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-11-19 US claimed
EP-0050856-B1 NEW PEPTIDE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-27 EP claimed
EP-0115816-A1 New aminoglycoside derivatives, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-08-15 EP claimed
EP-0050856-A2 New peptide, process for its preparation and pharmaceutical composition containing it FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-05-05 EP claimed
US-4057530-A STABILIZERS FOR VINYL CHLORIDE POLYMERS LABAZ (FR) 1977-11-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240175031-A1 TREATMENT OF MST1 RELATED DISEASES AND DISORDERS MST1, MST1R, MSTN TSHR 1312/4885THRB 238/4885PTPN7 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.