Urea

Urea

SCHEMBL6942842

NC(=O)NN1CCNC1.NC(N)=O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34371 0.98
SCHEMBL28189279 0.96 GNAI3 (0.34) GNAI3GNAO1GNAI1CA12CA1
SCHEMBL7527875 0.96 GNAI3 (0.34) GNAI3GNAO1GNAI1CA12CA1
SCHEMBL27888790 0.96 GNAI3 (0.34) GNAI3GNAO1GNAI1CA12CA1
Ammonia Solution, Strong SCHEMBL28242181 0.96 GNAI3 (0.34) GNAI3GNAO1GNAI1CA12CA1
Nitrogen SCHEMBL20898038 0.94 GNAI3 (0.33) GNAI3GNAO1GNAI1
Sulfurous Acid SCHEMBL27541437 0.89 GNAI3 (0.31) GNAI3GNAO1GNAI1
SCHEMBL28245244 0.89 GNAI3 (0.31) GNAI3GNAO1GNAI1
Sulfuric Acid SCHEMBL28115597 0.87 GNAI3 (0.30) GNAI3GNAO1GNAI1
Propene SCHEMBL27563440 0.87 GNAI3 (0.33) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114306162-A Production and preparation process and application of plant extract for cosmetics 广州酚酞生物科技有限公司 2022-04-12 CN disclosed
CN-103237486-A Wipe coated with botanical emulsion having anitmicrobial properties KIMBERLY CLARK CO 2013-08-07 CN disclosed
CN-1662216-A Skin conditioning composition containing compounds which mimic the effects of retinoic acid on skin UNILEVER NV (NL) 2005-08-31 CN disclosed
CN-1553794-A Stable skin conditioning compositions containing retinoid boosters 2004-12-08 CN disclosed
CN-1538833-A Mild cosmetic compositions containing stabilized retinoids 2004-10-20 CN disclosed
CN-1482898-A Stable skin care product containing a retinoid and a retinoid booster system in a dual compartment package 2004-03-17 CN disclosed
CN-1482899-A Skin care product containing retinoids, retinoid booster and phytoestrogens in a dual compartment package 2004-03-17 CN disclosed
EP-1351651-A2 MILD COSMETIC COMPOSITION WITH STABILIZED RETINOIDS UNILEVER PLC (GB) 2003-10-15 EP disclosed
EP-1349536-A2 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM UNILEVER PLC (GB) 2003-10-08 EP disclosed
EP-1345586-A2 STABLE SKIN CARE PRODUCT CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM IN A DUAL COMPARTMENT PACKAGE UNILEVER PLC (GB) 2003-09-24 EP disclosed
EP-1345568-A2 STABLE SKIN CONDITIONING COMPOSITIONS CONTAINING RETINOID BOOSTERS UNILEVER PLC (GB) 2003-09-24 EP disclosed
EP-1333800-A2 SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 2003-08-13 EP disclosed
WO-2002053123-A2 STABLE SKIN CARE PRODUCT CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM IN A DUAL COMPARTMENT PACKAGE UNILEVER PLC (GB) 2002-07-11 WO disclosed
WO-2002053125-A2 SKIN CARE PRODUCT CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM IN A DUAL COMPARTMENT PACKAGE UNILEVER PLC (GB) 2002-07-11 WO disclosed
WO-2002053124-A2 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM UNILEVER PLC (GB) 2002-07-11 WO disclosed
WO-2002053089-A2 STABLE SKIN CONDITIONING COMPOSITIONS CONTAINING RETINOID BOOSTERS UNILEVER PLC (GB) 2002-07-11 WO disclosed
WO-2002041849-A2 MILD COSMETIC COMPOSITION WITH STABILIZED RETINOIDS UNILEVER PLC (GB) 2002-05-30 WO disclosed
WO-2002002074-A2 SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 2002-01-10 WO disclosed