Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948327 | 0.82 | HSD17B10 (0.54) | NAMPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL6950893 | 0.81 | GAA (0.47) | KDM4EALDH1A1 | |
| SCHEMBL6947210 | 0.68 | NTRK3 (0.47) | NAMPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL6770247 | 0.68 | ALDH1A1 (0.46) | NAMPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL1070561 | 0.66 | KDM4E (0.62) | NAMPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL30352289 | 0.66 | KDM4E (0.62) | NAMPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL349933 | 0.64 | NAMPT (0.80) | NAMPTKDM4ELMNAHTT | |
| SCHEMBL29457342 | 0.64 | NAMPT (0.80) | NAMPTKDM4ELMNAHTT | |
| SCHEMBL241619 | 0.64 | NPC1 (0.63) | NAMPTHSD17B10TP53MAPK1ALDH1A1 | |
| SCHEMBL30737600 | 0.63 | NPC1 (0.61) | NAMPTHSD17B10TP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | claimed |