SCHEMBL6943196

SCHEMBL6943196

CCOC(=O)[C@H](C)OC(=O)O[C@@H](C)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SOAT1 P35610 1/20 0.46
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TRPA1 O75762 1/20 0.37
KMT2A Q03164 2/20 0.36
PIN1 Q13526 1/20 0.34
HPGD P15428 1/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28391087 1.00 ALDH1A1 (0.50) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL26739691 0.93 ALDH1A1 (0.44) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL21983314 0.93 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL10011713 0.91 ALDH1A1 (0.46) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL22556036 0.83 ALDH1A1 (0.39) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL12150159 0.83 ALDH1A1 (0.39) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL6943200 0.83 ALDH1A1 (0.42) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL12150070 0.83 ALDH1A1 (0.42) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL725208 0.83 ALDH1A1 (0.52) ALDH1A1SOAT1LMNAHSD17B10ALOX15
SCHEMBL6906507 0.83 ALDH1A1 (0.52) ALDH1A1SOAT1LMNAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973768-B1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-09 EP disclosed
US-6407129-B1 INJECTABLE QUATERNIZED SALT FUNGICIDES; WATER SOLUBILITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-1120116-A1 ANTIMYCOTIC DRUG COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP disclosed