Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946209 | 0.92 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL21405667 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL21405666 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL4683648 | 0.83 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL6939603 | 0.83 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL10833327 | 0.81 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL6945044 | 0.81 | KMT2A (0.51) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL21405675 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL21405676 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL8664843 | 0.76 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083175-B1 | Triazole derivatives having antifungal activity | SANKYO CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6392082-B1 | CHEMICAL INTERMEDIATE | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6391903-B1 | THERAPY FOR FUNGI INFECTIONS | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6337403-B1 | CRYSTALLINE FORM OF A PHARMACEUTICAL COMPOSITION CONTAINING SAID DERIVATIVES WITH TREATING AND PREVENTING FUNGAL INFECTIONS USING BUTADIENE FLUORO BENZONITRILE GROUPS | SANKYO COMPANY, LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1083175-A2 | Triazole derivatives having antifungal activity | Sankyo Company Limited (JP) | 2001-03-14 | — | — | EP | disclosed |