Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683648 | 0.85 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL6939603 | 0.85 | CYP3A4 (0.52) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL6946209 | 0.82 | CYP3A4 (0.46) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL8811243 | 0.81 | KMT2A (0.57) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL8811239 | 0.81 | KMT2A (0.57) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL6943199 | 0.81 | CYP3A4 (0.43) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9202358 | 0.80 | KMT2A (0.54) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9005054 | 0.80 | KMT2A (0.54) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9826655 | 0.80 | KMT2A (0.56) | KMT2ACYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9792922 | 0.79 | KMT2A (0.55) | KMT2ACYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083175-B1 | Triazole derivatives having antifungal activity | SANKYO CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6392082-B1 | CHEMICAL INTERMEDIATE | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-1083175-A2 | Triazole derivatives having antifungal activity | Sankyo Company Limited (JP) | 2001-03-14 | — | — | EP | disclosed |