Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6949525 | 0.92 | MEN1 (0.48) | MEN1KMT2AATMALDH1A1MAPT | |
| Fumaric Acid SCHEMBL6949519 | 0.92 | MEN1 (0.48) | MEN1KMT2AATMALDH1A1MAPT | |
| Fumaric Acid SCHEMBL8671252 | 0.91 | MEN1 (0.48) | MEN1KMT2AATMALDH1A1MAPT | |
| Fumaric Acid SCHEMBL8671251 | 0.91 | MEN1 (0.48) | MEN1KMT2AATMALDH1A1MAPT | |
| SCHEMBL6946854 | 0.86 | SLC6A4 (0.54) | MEN1KMT2ACYP19A1TBXAS1TBXA2R | |
| SCHEMBL6948560 | 0.86 | SLC6A4 (0.54) | ALDH1A1TSHRCYP19A1TBXAS1TBXA2R | |
| SCHEMBL6950410 | 0.86 | TBXA2R (0.58) | CYP19A1TBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL8666242 | 0.85 | SLC6A4 (0.53) | MEN1KMT2ACYP19A1TBXAS1TBXA2R | |
| SCHEMBL6948590 | 0.83 | CYP1A2 (0.56) | MEN1KMT2AATMTBXAS1TBXA2R | |
| Hydrochloric Acid SCHEMBL6949500 | 0.83 | CYP1A2 (0.55) | MEN1KMT2AATMTBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | claimed |
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0709378-A2 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-05-01 | — | — | EP | disclosed |