Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840343 | 0.79 | MEN1 (0.65) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL667594 | 0.78 | MEN1 (0.64) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL20524290 | 0.78 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL806523 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL5686801 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL7030942 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL1748538 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL22010907 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL2345370 | 0.77 | MEN1 (1.00) | MEN1KMT2AAPAF1LMNAKDM4E | |
| SCHEMBL27267264 | 0.77 | MEN1 (0.63) | MEN1KMT2AAPAF1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144380-A4 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA (JP) | 2003-11-26 | — | — | EP | claimed |
| CN-1376145-A | A meta-nitro phenol derivative and a process for producing it | ISHIHARA SANGYO KAISHA (JP) | 2002-10-23 | — | — | CN | claimed |
| EP-1144380-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-17 | — | — | EP | claimed |
| WO-2000032573-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-06-08 | — | — | WO | claimed |
| CN-108864076-A | glucosylceramide synthase inhibitors | 建新公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-105073745-A | Glucosylceramide synthase inhibitors | GENZYME CORP | 2015-11-18 | — | — | CN | disclosed |
| EP-1144380-A4 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA (JP) | 2003-11-26 | — | — | EP | disclosed |
| CN-1376145-A | A meta-nitro phenol derivative and a process for producing it | ISHIHARA SANGYO KAISHA (JP) | 2002-10-23 | — | — | CN | disclosed |
| EP-1144380-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000032573-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-06-08 | — | — | WO | disclosed |