SCHEMBL6943828

SCHEMBL6943828

Nc1nc2ncn(C[C@]3(CO)C[C@H]3CO)c2c(=O)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.37
BLM P54132 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
NFKB1 P19838 1/20 0.37
VCP P55072 1/20 0.37
HIF1A Q16665 1/20 0.37
TK1 P04183 2/20 0.37
PNP P00491 4/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.36
EDNRA P25101 1/20 0.36
HTR2A P28223 1/20 0.36
RECQL P46063 1/20 0.36
HBB P68871 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17591528 0.82 TK1 (0.55) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL4550680 0.82 TK1 (0.55) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL9260998 0.82 TK1 (0.55) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL7453741 0.82 TK1 (0.55) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL4550681 0.82 TK1 (0.55) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL8053194 0.81 TK1 (0.54) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL8067159 0.81 TK1 (0.54) ADORA3BLMALDH1A1SMN1; SMN2KMT2A
SCHEMBL9263234 0.80
SCHEMBL7453892 0.80
SCHEMBL7453078 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890574-B1 Method for purifying nucleic acid derivatives AJINOMOTO KK (JP) 2003-03-12 EP claimed
US-6114525-A Method for purifying nucleic acid derivatives AJINOMOTO CO., INC. (JP) 2000-09-05 US claimed
US-6114525-A Method for purifying nucleic acid derivatives AJINOMOTO CO., INC. (JP) 2000-09-05 US disclosed
US-6114525-A Method for purifying nucleic acid derivatives AJINOMOTO CO., INC. (JP) 2000-09-05 US disclosed