Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 2/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SHBG | P04278 | 3/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839775 | 1.00 | G6PD (0.60) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL6839778 | 1.00 | G6PD (0.60) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL1418980 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL1418644 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL6905401 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL1418928 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL1419111 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL6874636 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL6884657 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 | |
| SCHEMBL1500304 | 0.88 | G6PD (0.77) | G6PDGPBAR1LMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351971-A2 | COMPOUNDS USEFUL FOR TREATING HYPERTRIGLYCERIDEMIA | Aeson Therapeutics Inc. (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002028880-A2 | COMPOUNDS USEFUL FOR TREATING HYPERTRIGLYCERIDEMIA | AESON THERAPEUTICS INC. (US) | 2002-04-11 | — | — | WO | disclosed |