Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944321 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL7076006 | 0.95 | MAPT (0.61) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6943333 | 0.92 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6939699 | 0.92 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6939693 | 0.92 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6941788 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6939339 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL7563245 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL6939398 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD | |
| SCHEMBL7564054 | 0.85 | MAPT (0.61) | ALDH1A1MAPTPOLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-B1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6384080-B1 | TREATMENT AND/OR PREVENTION OF CERTAIN CARDIOVASCULAR DISORDERS, UROGENITAL DISORDERS, RESPIRATORY SYSTEM DISORDERS, DISORDERS OF GUT MOTILITY, SEXUAL DISORDERS, DIABETIC COMPLICATIONS, URTICARIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |