Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26122888 | 0.92 | SLC22A6 (0.32) | SLC22A6SMN1; SMN2 | |
| SCHEMBL7777306 | 0.78 | SLC22A6 (0.41) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL18837936 | 0.75 | SLC22A6 (0.57) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL16390622 | 0.73 | — | — | |
| SCHEMBL16390625 | 0.73 | — | — | |
| SCHEMBL7775608 | 0.72 | SMN1; SMN2 (0.39) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL6939324 | 0.71 | APP (0.34) | SMN1; SMN2TDP1 | |
| SCHEMBL15104832 | 0.71 | TDP1 (0.39) | SLC22A6LMNATDP1 | |
| SCHEMBL9175298 | 0.71 | TDP1 (0.39) | SLC22A6LMNATDP1 | |
| SCHEMBL28351660 | 0.70 | SLC22A6 (0.32) | SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772771-B2 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-0772771-B1 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0959352-A1 | Determining biodegradability of aspartic acid derivatives, degradable chelants, uses and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1999-11-24 | — | — | EP | disclosed |