Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775613 | 0.84 | ECE1 (0.33) | TP53 | |
| SCHEMBL24711911 | 0.79 | ENPEP (0.35) | SMN1; SMN2TP53MAPT | |
| SCHEMBL24711726 | 0.78 | CYP2D6 (0.34) | MAPT | |
| SCHEMBL7777306 | 0.78 | SLC22A6 (0.41) | SMN1; SMN2SLC22A6TDP1MAPTGABRR1 | |
| SCHEMBL2913318 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL11269612 | 0.76 | TDP1 (0.40) | SMN1; SMN2SLC22A6TDP1EPORPGR | |
| SCHEMBL1172848 | 0.76 | TDP1 (0.40) | SMN1; SMN2SLC22A6TDP1EPORPGR | |
| SCHEMBL5494621 | 0.75 | BHMT (0.34) | SMN1; SMN2TDP1EPOR | |
| SCHEMBL7777426 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2SLC22A6TDP1TP53MAPT | |
| SCHEMBL629343 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2SLC22A6TDP1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127153-A1 | METHOD OF PRODUCING ASPARTIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026398-A1 | METHOD OF PRODUCING ASPARTIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |