Biphenyl

Biphenyl

SCHEMBL6944626

C1CCC(C2CCCCC2)CC1.O=C1C=CC(=O)N1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.55
GSK3B P49841 1/20 0.55
CCR6 P51684 1/20 0.55
MAPT P10636 3/20 0.43
ALDH1A1 P00352 6/20 0.40
DAO P14920 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596092 0.84 GSK3A (0.79) GSK3AGSK3BCCR6ALDH1A1
Cyclopentane SCHEMBL29123251 0.84 GSK3A (0.79) GSK3AGSK3BCCR6ALDH1A1
Cyclohexane SCHEMBL28392500 0.84 GSK3A (0.79) GSK3AGSK3BCCR6ALDH1A1
Cyclohexane SCHEMBL19996052 0.84 GSK3A (0.79) GSK3AGSK3BCCR6ALDH1A1
SCHEMBL29010798 0.81 GSK3A (0.50) GSK3AGSK3BCCR6MAPTALDH1A1
SCHEMBL29010973 0.81 GSK3A (0.50) GSK3AGSK3BCCR6MAPTALDH1A1
SCHEMBL4938638 0.81 GSK3A (0.50) GSK3AGSK3BCCR6MAPTALDH1A1
SCHEMBL9514628 0.79 GSK3A (0.48) GSK3AGSK3BCCR6MAPTDAO
SCHEMBL10589613 0.79 GSK3A (0.48) GSK3AGSK3BCCR6MAPTDAO
Methylcyclopentane SCHEMBL29010800 0.78 GSK3A (0.52) GSK3AGSK3BCCR6MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1067151-B1 HEAT-EXPANDABLE MICROCAPSULES AND METHOD OF UTILIZING THE SAME MATSUMOTO YUSHI SEIYAKU KK (JP) 2003-12-17 EP disclosed
US-6235800-B1 Heat-expandable microcapsules and method of utilizing the same MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2001-05-22 US disclosed
EP-1067151-A1 HEAT-EXPANDABLE MICROCAPSULES AND METHOD OF UTILIZING THE SAME MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2001-01-10 EP disclosed