Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010973 | 1.00 | GSK3A (0.50) | GSK3AGSK3BCCR6MAPTKMT2A | |
| SCHEMBL4938638 | 1.00 | GSK3A (0.50) | GSK3AGSK3BCCR6MAPTKMT2A | |
| Methylcyclopentane SCHEMBL29010800 | 0.98 | GSK3A (0.52) | GSK3AGSK3BCCR6MAPTKMT2A | |
| Bicarbonate SCHEMBL9841170 | 0.92 | GSK3A (0.42) | GSK3AGSK3BCCR6MAPTKMT2A | |
| SCHEMBL29010977 | 0.91 | GSK3A (0.55) | GSK3AGSK3BCCR6MAPTKMT2A | |
| SCHEMBL29010933 | 0.85 | GSK3A (0.61) | GSK3AGSK3BCCR6CRBN | |
| Biphenyl SCHEMBL6944626 | 0.81 | GSK3A (0.55) | GSK3AGSK3BCCR6MAPTKMT2A | |
| Cyclohexane SCHEMBL28392500 | 0.80 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBNALDH1A1 | |
| Cyclopentane SCHEMBL29123251 | 0.80 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBNALDH1A1 | |
| SCHEMBL11596092 | 0.80 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |