Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30433987 | 1.00 | GAA (0.70) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11416116 | 0.90 | CYP1A2 (0.61) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11221918 | 0.87 | ALDH1A1 (0.52) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL29533603 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL351594 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL350548 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL30296935 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL17240308 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL22773397 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL368123 | 0.87 | TSHR (0.56) | GAAMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334407-A1 | BUNTE SALTS FROM AMINO ACIDS AND OLIGOPEPTIDES AS PROTECTIVE INGREDIENTS IN HAIR TREATMENT MEANS | Henkel AG & Co. KGaA (DE) | 2018-06-20 | — | — | EP | disclosed |
| CN-106999387-A | Dye composition comprising p-phenylenediamine oxidation base and additional base | 莱雅公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106999395-A | Dye composite comprising p-phenylenediamine fouramine and specific coupling agent | 莱雅公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106999388-A | Dye composite comprising p-phenylenediamine fouramine and heterocycle fouramine | 莱雅公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-1301163-A1 | OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002005767-A1 | OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-01-24 | — | — | WO | disclosed |
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4065449-A | Tetrachloro substituted disazo pigments | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-3978038-A | POLYAMIDES, POLYESTERS, POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3956266-A | DISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |