Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944931 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6943733 | 0.93 | MAPT (0.58) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6939374 | 0.93 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6939369 | 0.93 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6941990 | 0.93 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6940658 | 0.93 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6943845 | 0.92 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6943217 | 0.91 | MAPT (0.56) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6946578 | 0.90 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6946648 | 0.90 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-B1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |