Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944432 | 1.00 | MAPT (0.44) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6944427 | 1.00 | MAPT (0.44) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6938952 | 0.96 | LMNA (0.45) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6938956 | 0.96 | LMNA (0.45) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6938938 | 0.90 | NPSR1 (0.48) | MAPTKMT2ANPSR1L3MBTL1LMNA | |
| SCHEMBL6938934 | 0.90 | NPSR1 (0.48) | MAPTKMT2ANPSR1L3MBTL1LMNA | |
| SCHEMBL6942691 | 0.90 | NPSR1 (0.48) | MAPTKMT2ANPSR1L3MBTL1LMNA | |
| SCHEMBL6940791 | 0.88 | SSTR5 (0.46) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6939759 | 0.88 | LMNA (0.46) | MAPTKMT2ANPBWR1MCHR1NPSR1 | |
| SCHEMBL6939757 | 0.88 | LMNA (0.46) | MAPTKMT2ANPBWR1MCHR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-B1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |