Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951691 | 0.89 | MTNR1A (0.61) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL2633259 | 0.87 | KDM4E (0.79) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL674415 | 0.87 | KDM4E (1.00) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL1461935 | 0.86 | KDM4E (0.77) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL2686551 | 0.86 | KDM4E (0.77) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL1395687 | 0.86 | KDM4E (0.77) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| Hydrochloric Acid SCHEMBL5013119 | 0.84 | KDM4E (0.75) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL11746973 | 0.84 | KDM4E (0.80) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL2625194 | 0.84 | KDM4E (0.75) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL14665122 | 0.84 | KDM4E (0.75) | KDM4EGPR84MTNR1AMTNR1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824544-B1 | PEPTIDYL COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-04-16 | — | — | EP | claimed |