Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929768 | 0.90 | CTSB (0.56) | CTSBSPPL2ATRPM8CTRB1TACR1 | |
| SCHEMBL5929818 | 0.90 | CTSB (0.56) | CTSBSPPL2ATRPM8CTRB1TACR1 | |
| SCHEMBL6443918 | 0.88 | CTSB (0.57) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL6443922 | 0.88 | CTSB (0.57) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL6712703 | 0.85 | MLNR (0.55) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL6443553 | 0.85 | MLNR (0.55) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL6443555 | 0.85 | MLNR (0.55) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL8331508 | 0.85 | CTSB (0.54) | CTSBSPPL2ATRPM8MLNRNR1I2 | |
| SCHEMBL6447570 | 0.85 | CTSB (0.66) | CTSBSPPL2ATRPM8CTRB1PSEN1 | |
| SCHEMBL6447573 | 0.85 | CTSB (0.66) | CTSBSPPL2ATRPM8CTRB1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633881-B1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LTD (HK) | 2003-10-29 | — | — | EP | claimed |
| EP-0633881-B1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LTD (HK) | 2003-10-29 | — | — | EP | disclosed |