Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.79 |
| ▸ | FLT3 | P36888 | 7/20 | 0.79 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.79 |
| ▸ | SRC | P12931 | 1/20 | 0.79 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.78 |
| ▸ | CDK1 | P06493 | 11/20 | 0.78 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.78 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.78 |
| ▸ | CDK4 | P11802 | 4/20 | 0.78 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.78 |
| ▸ | CCND1 | P24385 | 4/20 | 0.78 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.78 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.73 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6945276 | 0.99 | CDK2 (0.78) | CDK2FLT3PDGFRASRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6945271 | 0.99 | CDK2 (0.78) | CDK2FLT3PDGFRASRCCCNE1 | |
| Hydrochloric Acid SCHEMBL27479416 | 0.99 | CDK2 (0.78) | CDK2FLT3PDGFRASRCCCNE1 | |
| SCHEMBL27538554 | 0.91 | FLT3 (0.80) | CDK2FLT3PDGFRASRCCCNE1 | |
| SCHEMBL5194936 | 0.89 | CDK2 (0.85) | CDK2FLT3PDGFRASRCCCNE1 | |
| SCHEMBL5195342 | 0.89 | CDK2 (0.73) | CDK2FLT3PDGFRASRCCCNE1 | |
| SCHEMBL5195307 | 0.89 | CDK2 (0.85) | CDK2FLT3PDGFRASRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6821007 | 0.89 | CDK2 (0.81) | CDK2FLT3PDGFRASRCCCNE1 | |
| Hydrochloric Acid SCHEMBL6821008 | 0.89 | CDK2 (0.81) | CDK2FLT3PDGFRASRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5195826 | 0.88 | CDK2 (0.83) | CDK2FLT3PDGFRASRCCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143858-C | 6, 9-disubstituted 2- [ trans- (aminocyclohexyl) amino ] purines, compositions and uses thereof | ������ҩ������˾ | 2004-03-31 | — | — | CN | claimed |
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | claimed |
| CN-1292789-A | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AWANDIS PHARMACEUTICAL CORP (US) | 2001-04-25 | — | — | CN | claimed |