Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950519 | 0.88 | MME (0.42) | ADAM17MMETAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL16487289 | 0.84 | MME (0.43) | MMETAS1R3TAS1R1SMN1; SMN2BIRC2 | |
| SCHEMBL9911582 | 0.80 | SMN1; SMN2 (0.44) | ADAM17MMETAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL12868880 | 0.80 | SMN1; SMN2 (0.44) | ADAM17MMETAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL5514853 | 0.80 | SMN1; SMN2 (0.44) | ADAM17MMETAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL6800777 | 0.79 | MME (0.45) | MMETAS1R3TAS1R1SMN1; SMN2FOLH1 | |
| SCHEMBL15015675 | 0.77 | MME (0.46) | MMETAS1R3TAS1R1SMN1; SMN2FOLH1 | |
| SCHEMBL6947237 | 0.77 | MME (0.39) | ADAM17MMETAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL14316099 | 0.75 | BIRC2 (0.41) | MMETAS1R3TAS1R1SMN1; SMN2BIRC2 | |
| SCHEMBL28312044 | 0.75 | MGAM (0.39) | MMETAS1R3TAS1R1SMN1; SMN2BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030842-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2003-04-02 | — | — | EP | disclosed |
| EP-0835240-B1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-11-02 | — | — | EP | disclosed |
| EP-1030842-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-08-30 | — | — | EP | disclosed |
| EP-0821668-B1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARM (GB) | 2000-08-23 | — | — | EP | disclosed |
| US-5919940-A | TERT-LEUCINE-THIAZOL-2-YLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5917090-A | INHIBIT TUMOR NECROSIS FACTOR; ANTIARTHRITIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5908851-A | TUMOR NECROSIS FACTOR, COLLAGENASE, STROMELYSIN, AND GELATINASE INHIBITORS; OSTEOPOROSIS, RHEUMATIC AND ORAL DISEASES; ANTIARTHRITIC AND ANTIULCER AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-01 | — | — | US | disclosed |
| WO-1999025693-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-05-27 | — | — | WO | disclosed |
| US-5859253-A | L-TERT-LEUCINE-2-PYRIDYLAMIDE | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747514-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |
| EP-0835240-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-15 | — | — | EP | disclosed |
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997003966-A1 | N-(AMINO ACID) SUBSTITUTED SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |
| WO-1997002239-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | disclosed |