Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.47 |
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22699047 | 0.82 | DPP7 (0.49) | DPP7DPP4DPP8DPP9FAAH | |
| SCHEMBL8484966 | 0.81 | ALDH1A1 (0.42) | DPP7CYP2C19EPHX2GAAKMT2A | |
| SCHEMBL12947853 | 0.80 | DPP4 (0.51) | DPP7DPP4DPP8DPP9CYP2C19 | |
| SCHEMBL16435175 | 0.80 | DPP4 (0.51) | DPP7DPP4DPP8DPP9CYP2C19 | |
| SCHEMBL8487517 | 0.79 | ALDH1A1 (0.46) | DPP7DPP4CYP2C19EPHX2GAA | |
| SCHEMBL6044953 | 0.78 | DPP7 (0.46) | DPP7DPP4DPP8DPP9FAAH | |
| SCHEMBL6945616 | 0.77 | DPP4 (0.43) | DPP7DPP4DPP8DPP9FAAH | |
| SCHEMBL8483742 | 0.76 | CYP3A4 (0.50) | CYP2C19GAAKMT2A | |
| SCHEMBL28071366 | 0.74 | DPP4 (0.82) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL28071368 | 0.74 | DPP4 (0.82) | DPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |