Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942715 | 1.00 | ADAM17 (0.59) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6948118 | 0.94 | ADAM17 (0.59) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6943561 | 0.94 | ADAM17 (0.67) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6945556 | 0.91 | ADAM17 (0.58) | ADAM17TGFBR1P2RX3 | |
| SCHEMBL6946725 | 0.91 | ADAM17 (0.56) | ADAM17TGFBR1P2RX3 | |
| SCHEMBL6947109 | 0.91 | ADAM17 (0.57) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6939910 | 0.91 | ADAM17 (0.57) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6939914 | 0.91 | ADAM17 (0.57) | ADAM17TGFBR1CTSCP2RX3 | |
| SCHEMBL6945793 | 0.91 | ADAM17 (0.55) | ADAM17TGFBR1P2RX3 | |
| SCHEMBL6942461 | 0.90 | ADAM17 (0.56) | ADAM17TGFBR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |