SCHEMBL6945928

SCHEMBL6945928

Cc1cccc(-n2c3ccc(C)cc3c3cc4c(cc32)c2cc(C)ccc2n4-c2cccc(C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MGLL Q99685 1/20 0.42
NOTUM Q6P988 1/20 0.41
MAT2A P31153 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PMM2 O15305 1/20 0.41
MPI P34949 1/20 0.41
PHOSPHO1 Q8TCT1 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
ADRB1 P08588 1/20 0.40
ACHE P22303 1/20 0.39
GAA P10253 2/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
AHR P35869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546854 0.96 TDP1 (0.45) TDP1HSP90AA1MGLLNOTUMMAT2A
SCHEMBL8282722 0.90 MEN1 (0.41) TDP1HSP90AA1MGLLNOTUML3MBTL1
SCHEMBL12799780 0.89 L3MBTL1 (0.52) TDP1HSP90AA1MGLLNOTUML3MBTL1
SCHEMBL17248311 0.89 KDM4E (0.47) NOTUMMAT2AL3MBTL1ALDH1A1HPGD
SCHEMBL2741408 0.87 L3MBTL1 (0.53) TDP1HSP90AA1MGLLNOTUMMAT2A
SCHEMBL26570018 0.87 BCHE (0.43) TDP1HSP90AA1MGLLNOTUMMAT2A
SCHEMBL6940379 0.87 KDM4E (0.52) MAT2AL3MBTL1ALDH1A1HPGDACHE
SCHEMBL16605577 0.87 MEN1 (0.39) TDP1HSP90AA1MGLLNOTUML3MBTL1
SCHEMBL20967606 0.86 L3MBTL1 (0.48) TDP1HSP90AA1MGLLNOTUML3MBTL1
SCHEMBL27058919 0.86 L3MBTL1 (0.48) TDP1HSP90AA1MGLLNOTUML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906947-B1 Indolocarbazole electroluminescent devices XEROX CORP (US) 2003-05-21 EP disclosed
EP-0906947-A1 Indolocarbazole electroluminescent devices XEROX CORPORATION (US) 1999-04-07 EP disclosed