SCHEMBL6946055

SCHEMBL6946055

[CH2]CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.68
LTB4R2 Q9NPC1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110386 0.85 LTB4R (0.68) LTB4RLTB4R2
SCHEMBL6756180 0.84 LTB4R (0.73) LTB4RLTB4R2
SCHEMBL6757528 0.84 LTB4R (0.71) LTB4RLTB4R2
SCHEMBL8987368 0.83 LTB4R (0.72) LTB4RLTB4R2
SCHEMBL8987039 0.81 LTB4R (1.00) LTB4R
SCHEMBL6759770 0.81 LTB4R (0.73) LTB4R
Ammonia Solution, Strong SCHEMBL6757534 0.80 LTB4R (0.73) LTB4RLTB4R2
SCHEMBL8987440 0.80 LTB4R (1.00) LTB4R
SCHEMBL6757530 0.80 LTB4R (1.00) LTB4R
SCHEMBL6760566 0.80 LTB4R (1.00) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1293214-A2 LTB4 antagonists and radiopharmaceuticals for imaging infection and inflammation Bristol-Myers Squibb Pharma Company (US) 2003-03-19 EP disclosed
EP-0999856-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION Du Pont Pharmaceuticals Company (US) 2000-05-17 EP disclosed
WO-1998015295-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION DUPONT PHARMACEUTICALS COMPANY (US) 1998-04-16 WO disclosed