Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946053 | 1.00 | MET (0.47) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6951516 | 0.91 | MET (0.44) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6951509 | 0.91 | MET (0.44) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6096893 | 0.87 | SMN1; SMN2 (0.54) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6096889 | 0.87 | SMN1; SMN2 (0.54) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6951842 | 0.86 | MET (0.48) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6951884 | 0.86 | MET (0.48) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6951847 | 0.86 | MET (0.48) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6952311 | 0.86 | MET (0.48) | METNFE2L2SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6952304 | 0.86 | MET (0.48) | METNFE2L2SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754682-B9 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-0754682-B1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5972976-A | FOR TREATMENT OF VARIOUS MALIGNANT TUMORS; (E)-4-(2-(2-(N-acetyl-N-((p-methoxyphenyl)sulfonyl)amino)phenyl)ethenyl)pyridine-1-oxide for example | NIPPON SHINYAKU COMPANY, LIMITED | 1999-10-26 | — | — | US | disclosed |
| EP-0754682-A1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-01-22 | — | — | EP | disclosed |