SCHEMBL6946068

SCHEMBL6946068

CC(O)Oc1ccc(N)cc1N.Nc1cccc(N)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 4/20 0.41
CYP3A4 P08684 3/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 8/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
TP53 P04637 2/20 0.41
POLB P06746 2/20 0.41
CASP7 P55210 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
ENPP2 Q13822 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129715 0.93 ALDH1A1 (0.46) CASP1CYP3A4ALDH1A1KDM4EMAPT
Hydrochloric Acid SCHEMBL3248993 0.91 ALDH1A1 (0.49) CASP1CYP3A4RECQLALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1426463 0.91 ALDH1A1 (0.49) CASP1CYP3A4RECQLALDH1A1KDM4E
Hydrochloric Acid SCHEMBL10397659 0.91 ALDH1A1 (0.49) CASP1CYP3A4RECQLALDH1A1KDM4E
Hydrochloric Acid SCHEMBL33975 0.91 ALDH1A1 (0.49) CASP1CYP3A4RECQLALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29836005 0.91 ALDH1A1 (0.49) CASP1CYP3A4RECQLALDH1A1KDM4E
3-Aminophenol SCHEMBL6422333 0.91 ALDH1A1 (0.52) CASP1CYP3A4RECQLALDH1A1KDM4E
SCHEMBL27706703 0.87 ALDH1A1 (0.33) CASP1CYP3A4RECQLALDH1A1KDM4E
Resorcinol SCHEMBL27716337 0.87 ALDH1A1 (0.43) CASP1CYP3A4ALDH1A1KDM4EMAPT
Hydrochloric Acid SCHEMBL10897913 0.87 ALDH1A1 (0.42) CASP1CYP3A4ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999203-B1 Novel developer in oxidative hair dyeing CLAIROL INC (US) 2003-02-26 EP claimed