⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231975 | 0.76 | LAP3 (0.39) | — | |
| SCHEMBL2430320 | 0.75 | — | — | |
| SCHEMBL18042445 | 0.73 | — | — | |
| SCHEMBL2148521 | 0.72 | LAP3 (0.36) | — | |
| SCHEMBL5054821 | 0.70 | — | — | |
| Phosphoric Acid SCHEMBL10804224 | 0.70 | — | — | |
| Phosphoric Acid SCHEMBL30622468 | 0.70 | — | — | |
| SCHEMBL242135 | 0.67 | — | — | |
| Phosphoric Acid SCHEMBL1831540 | 0.67 | — | — | |
| SCHEMBL6257829 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039887-A4 | METHODS FOR TREATMENT OF NEURO- AND NEPHRO-DISORDERS AND THERAPEUTIC TOXICITIES USING AMINOTHIOL COMPOUNDS | MEDIMMUNE ONCOLOGY INC (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-1039887-A1 | METHODS FOR TREATMENT OF NEURO- AND NEPHRO-DISORDERS AND THERAPEUTIC TOXICITIES USING AMINOTHIOL COMPOUNDS | U.S. BIOSCIENCE, INC. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999029312-A1 | METHODS FOR TREATMENT OF NEURO- AND NEPHRO-DISORDERS AND THERAPEUTIC TOXICITIES USING AMINOTHIOL COMPOUNDS | U.S. BIOSCIENCE, INC. (US) | 1999-06-17 | — | — | WO | disclosed |