Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.51 |
| ▸ | ATIC | P31939 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12960392 | 0.87 | CYP2C9 (0.66) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL9178619 | 0.85 | RPS6KA3 (0.54) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL8746224 | 0.85 | RPS6KA3 (0.54) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL6946358 | 0.84 | RPS6KA3 (0.56) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL6946360 | 0.84 | RPS6KA3 (0.56) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL27771162 | 0.84 | POLB (0.66) | RPS6KA3HSD17B10CYP2C9CYP2C19TSHR | |
| SCHEMBL1485997 | 0.83 | TSHR (0.75) | CA12CA2CA9RPS6KA3CYP2C9 | |
| SCHEMBL5752505 | 0.83 | TSHR (0.75) | CA12CA2CA9RPS6KA3CYP2C9 | |
| SCHEMBL29378452 | 0.83 | EGFR (0.69) | CA12CA2CA9RPS6KA3HSD17B10 | |
| SCHEMBL112102 | 0.83 | EGFR (0.69) | CA12CA2CA9RPS6KA3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261587-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIV BASEL (CH) | 2003-07-16 | — | — | EP | disclosed |
| EP-1261587-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Universität Basel (CH) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001040194-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT BASEL (CH) | 2001-06-07 | — | — | WO | disclosed |