Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATIC | P31939 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946360 | 1.00 | RPS6KA3 (0.56) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL6946362 | 0.84 | CA12 (0.57) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL27771162 | 0.84 | POLB (0.66) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL112102 | 0.83 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL29378452 | 0.83 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL112101 | 0.83 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL144370 | 0.81 | EGFR (0.67) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL144372 | 0.81 | EGFR (0.67) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL5364165 | 0.80 | RPS6KA3 (0.62) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC | |
| SCHEMBL31525881 | 0.77 | RPS6KA3 (0.58) | RPS6KA3CYP2C9CYP2C19HSD17B10ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261587-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIV BASEL (CH) | 2003-07-16 | — | — | EP | disclosed |
| EP-1261587-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Universität Basel (CH) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001040194-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT BASEL (CH) | 2001-06-07 | — | — | WO | disclosed |