Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 4/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953084 | 0.94 | MAOB (0.62) | MAOBHTR1A | |
| SCHEMBL13469510 | 0.92 | HTR1A (0.79) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL1532232 | 0.89 | MAOB (0.73) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL14028451 | 0.88 | HTR1A (0.79) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL29511230 | 0.88 | CHRM2 (0.61) | — | |
| SCHEMBL149620 | 0.88 | CHRM2 (0.61) | — | |
| Hydrochloric Acid SCHEMBL10957581 | 0.86 | CHRM2 (0.59) | — | |
| SCHEMBL3440240 | 0.85 | MAOB (0.73) | MAOBHTR1ADRD2 | |
| SCHEMBL1569172 | 0.85 | HTR1A (0.69) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL10857215 | 0.84 | HTR1A (0.68) | MAOBHTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |