Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728346 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL9199841 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL9727869 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL9728425 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL9727808 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL9205704 | 0.88 | GAA (0.48) | GAAALDH1A1L3MBTL1MAPK1KCNJ1 | |
| SCHEMBL6945782 | 0.84 | MMP9 (0.42) | GAAKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9127639 | 0.82 | KCNJ1 (0.41) | GAAALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8437967 | 0.82 | KCNJ1 (0.40) | KCNJ1KCNH2 | |
| SCHEMBL8438088 | 0.82 | KCNJ1 (0.40) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |