Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947047 | 1.00 | KMT2A (0.41) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL12589813 | 0.85 | KMT2A (0.44) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL2059320 | 0.85 | KMT2A (0.44) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL9686556 | 0.83 | UCHL1 (0.44) | KMT2AMEN1ACEKDM4EPKM | |
| SCHEMBL28721184 | 0.81 | HTRA1 (0.54) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL3053308 | 0.78 | MEN1 (0.42) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL6787235 | 0.78 | MEN1 (0.42) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL3053306 | 0.78 | MEN1 (0.42) | KMT2AMEN1CACNA1ACACNA2D1CACNB1 | |
| SCHEMBL699296 | 0.78 | KDM4E (0.43) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24023380 | 0.77 | HPGD (0.46) | KMT2AMEN1ALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |