SCHEMBL6947110

SCHEMBL6947110

c1ccc(Sc2cc(Sc3ccccc3)cc(Sc3ccccc3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
MAOB P27338 3/20 0.50
HPGD P15428 3/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MGLL Q99685 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HTR2C P28335 2/20 0.46
HTR6 P50406 1/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 2/20 0.43
MCL1 Q07820 2/20 0.42
BCL2 P10415 1/20 0.42
SLC6A4 P31645 1/20 0.41
RHEB Q15382 1/20 0.39
CHRNA7 P36544 1/20 0.39
NR1H2 P55055 1/20 0.38
DDAH1 O94760 1/20 0.38
NOS1 P29475 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3889754 0.90 HTR2C (0.56) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL3893269 0.90 HTR2C (0.56) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL9557022 0.90 HTR2C (0.56) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL3894071 0.90 HTR2C (0.56) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27611905 0.89 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL452 0.89 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL7109540 0.89 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL28332331 0.89 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27714827 0.89 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL3904216 0.88 MAOA (0.56) MAOAMAOBHPGDMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030085387-A1 Optical materials and optical part each containing aromatic sulfide compound and aromatic sulfide compound MITSUI CHEMICALS, INC. (JP) 2003-05-08 US disclosed
EP-1291679-A1 OPTICAL MATERIAL AND OPTICAL PART EACH CONTAINING AROMATIC SULFIDE COMPOUND AND AROMATIC SULFIDE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-03-12 EP disclosed