Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316191 | 1.00 | GPR84 (0.48) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL16684259 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL12372046 | 0.90 | — | — | |
| SCHEMBL12697091 | 0.87 | CES1 (0.48) | CES1CES2LMNAALDH1A1TSHR | |
| SCHEMBL1982596 | 0.82 | CES1 (0.43) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL13941288 | 0.81 | CES1 (0.68) | GPR84FFAR1FFAR4CES1CES2 | |
| SCHEMBL12198774 | 0.81 | CES1 (0.68) | GPR84FFAR1FFAR4CES1CES2 | |
| SCHEMBL8758526 | 0.81 | CES1 (0.68) | GPR84FFAR1FFAR4CES1CES2 | |
| SCHEMBL12198772 | 0.81 | CES1 (0.68) | GPR84FFAR1FFAR4CES1CES2 | |
| SCHEMBL3678184 | 0.81 | CES1 (0.42) | GPR84CES1CES2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084131-B1 | ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS | KURARAY CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6458868-B1 | Organophosphorus compounds for dental polymerizable compositions | KURARAY CO., LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1084131-A1 | ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS | KURARAY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| WO-2000058316-A1 | ORGANOPHOSPHORUS COMPOUNDS FOR DENTAL POLYMERIZABLE COMPOSITIONS | KURARAY CO., LTD. (JP) | 2000-10-05 | — | — | WO | disclosed |