Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738798 | 0.84 | BLM (0.52) | BLMLMNAHDAC8HDAC3HDAC4 | |
| SCHEMBL10290507 | 0.82 | BLM (0.48) | BLMLMNAHDAC8HDAC3HDAC4 | |
| SCHEMBL21008657 | 0.82 | HDAC3 (0.50) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10630172 | 0.81 | BLM (0.48) | BLMLMNAHDAC8HDAC3HDAC4 | |
| SCHEMBL12377272 | 0.80 | BLM (0.47) | BLMLMNAHDAC8HDAC3HDAC4 | |
| SCHEMBL10266718 | 0.80 | BLM (0.47) | BLMLMNAHDAC8HDAC3HDAC4 | |
| SCHEMBL62131 | 0.78 | BLM (0.46) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL10602150 | 0.78 | BLM (0.50) | BLMLMNAHDAC8HDAC3HDAC4 | |
| Phytanic Acid SCHEMBL3819827 | 0.77 | BLM (0.63) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL12713322 | 0.77 | BLM (0.57) | BLMLMNAMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138181-A1 | Phytanic acid derivative compositions and method of treating and/or preventing diabetes mellitus | ROCHE VITAMINS INC. | 2004-07-15 | — | — | US | claimed |
| US-20020082298-A1 | Phytanic acid derivative compositions and method of treating and/or preventing diabetes mellitus | F. HOFFMANN-LA ROCHE AG | 2002-06-27 | — | — | US | claimed |
| EP-1177789-A2 | Use of phytanic acid for the treatment of diabetes | Roche Vitamins AG (CH) | 2002-02-06 | — | — | EP | claimed |